Arsenic (Blood)
Measures arsenic levels in blood to detect recent exposure to this toxic heavy metal, useful for occupational or environmental monitoring.
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What this test measures
The arsenic blood test measures total arsenic levels in blood, which typically should not exceed 50 mcg/L in healthy individuals. Abnormal blood arsenic concentrations greater than 12 ng/mL indicate significant exposure but will only be detected immediately after exposure, as arsenic is not likely to be detected in blood specimens drawn more than 2 days after exposure.
Arsenic is a ubiquitous, naturally occurring metalloid that may be a significant risk factor for cancer after exposure to contaminated drinking water, cigarettes, foods, industry, occupational environment, and air. The half-life of inorganic arsenic in blood is 4 to 6 hours, and the half-life of the methylated metabolites is 20 to 30 hours. This test is primarily useful for monitoring recent or acute exposure rather than chronic exposure.
Who should consider this test
You might consider this test if you are experiencing any of the following:
- Individuals who work in industries that use or produce arsenic-containing materials, including smelting, mining, semiconductor manufacturing, glass production, or wood preservation.
- Those living near industrial areas or former industrial sites where arsenic contamination may have occurred.
- People with suspected recent arsenic exposure from contaminated drinking water, especially those using private wells in areas known for high groundwater arsenic levels.
- Individuals experiencing symptoms that may suggest arsenic poisoning, such as severe gastrointestinal symptoms, skin changes, or neurological symptoms after potential exposure.
- Workers in agriculture or landscaping who may be exposed to arsenic-containing pesticides or treated wood products.
What to expect
Preparation
Avoid eating seafood, fish, or shellfish for 48-72 hours before the test, as these foods naturally contain organic arsenic that can affect results. Discontinue nutritional supplements and vitamins if advised by your healthcare provider. No fasting is required.
Sample Type
A standard blood draw is performed using a special royal blue-top collection tube to prevent contamination from trace metals.
Collection
The blood sample is collected through a quick venipuncture procedure at the testing location and sent to the laboratory for analysis using specialized equipment.
Turnaround
Results are typically available within 1-3 business days after the laboratory receives your sample.
Understanding your results
Blood arsenic concentrations should not exceed 50 mcg/L, and this test is most effective for detecting recent exposure within days of contact. Abnormal concentrations greater than 12 ng/mL indicate significant exposure but will only be detected immediately after exposure since arsenic is not likely to be detected in blood specimens drawn more than 2 days after exposure.
| Population | Reference Range | Notes |
|---|---|---|
| Adults (all ages) | < 12 ng/mL (< 12 μg/L) | Normal background level with no significant recent exposure |
| Adults (unexposed) | 0.3-2 μg/L | Typical range in individuals with no known arsenic exposure |
Reference ranges may vary by laboratory and individual factors. Results should be interpreted by a healthcare provider in the context of your overall health.
What does a “Low” result mean?
Low or undetectable arsenic levels in blood typically indicate no recent significant exposure to arsenic. This is the expected result for individuals without occupational or environmental arsenic exposure. Blood is not considered a good specimen to screen for arsenic exposure, and urine is the preferred specimen for assessment of arsenic exposure.
What does a “High” result mean?
Elevated blood arsenic levels commonly range from several hundred to several thousand micrograms per liter in patients with arsenic poisoning. High levels may indicate recent exposure and can cause immediate symptoms including nausea, vomiting, and diarrhea, with long-term exposure potentially causing skin changes such as darkening and lesions. Potentially toxic ranges for blood arsenic are considered to be greater than or equal to 600 μg/L.
Privacy & confidentiality
Your arsenic test results are completely confidential and protected under HIPAA regulations. Results are not shared with employers, insurance companies, or added to your medical records unless you specifically request it. No doctor visit is required to order this test.
Frequently asked questions
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CPT Code: 83015, 82175
This test may not be available in: NY, NJ, RI
This page is for informational purposes only and does not constitute medical advice. Always consult with a healthcare provider regarding any health concerns. LevelPanel does not diagnose, treat, or prescribe.
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