Comprehensive Testosterone Test
A comprehensive hormone panel that measures total testosterone, free testosterone, SHBG, and albumin to provide the complete picture of testosterone availability and hormonal balance.
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What this test measures
This comprehensive testosterone panel includes measurements of albumin, sex hormone-binding globulin (SHBG), and total and free testosterone, providing a complete assessment of hormonal health. Total testosterone measures the total amount of testosterone in the blood, including both testosterone that's attached and not attached to proteins. However, only 0.5% to 3% of total testosterone is free and non-protein bound, which is the active form available for use by body tissues.
The test calculates free testosterone levels using the other measurements, as free testosterone is often calculated using total testosterone, SHBG, and albumin levels. Albumin and SHBG help regulate how much free testosterone is available for use, offering a clearer picture of free testosterone levels. Higher levels of SHBG may indicate lower levels of free testosterone available for the body's use, while lower SHBG levels may result in higher free testosterone levels. This comprehensive approach provides insight into not just how much testosterone is present, but how much is actually available for the body to use.
What's included
Who should consider this test
You might consider this test if you are experiencing any of the following:
- Men experiencing decreased energy, fatigue, or unexplained tiredness that may indicate low testosterone levels
- Men noticing changes in sex drive, difficulty with erections, or other sexual health concerns that could be hormone-related
- Men dealing with unexplained muscle loss, difficulty building or maintaining muscle mass, or changes in physical strength
- Men with symptoms of mood changes, irritability, or depression that may be linked to hormonal imbalances
- Men whose total testosterone results seemed normal but still experience symptoms that suggest low testosterone
- Men with metabolic concerns, weight gain, or conditions like diabetes that can affect hormone levels
- Men seeking a complete picture of their hormonal health rather than just basic testosterone measurements
What to expect
Preparation
No fasting is required for this test. Schedule your appointment for morning hours (7-10 AM) when possible, as testosterone levels are naturally highest in the morning. Avoid strenuous exercise for 24 hours before testing.
Sample Type
A healthcare professional will draw a small blood sample from a vein in your arm using a standard needle and collection tube
Collection
Visit your chosen LabCorp location with a photo ID. No appointment necessary at most locations - simply walk in during business hours. The blood draw typically takes less than 5 minutes
Turnaround
Results are typically available within 1-3 business days and will be delivered securely to your online account
Understanding your results
Reference ranges for total testosterone typically show values around 348-723 ng/dL for healthy adult men, while free testosterone ranges around 70-141 pg/mL. However, these ranges can vary between laboratories based on their methodology and patient population. Understanding albumin, SHBG, and testosterone levels together helps determine whether symptoms may be linked to high or low testosterone. The combination of all four measurements provides a more complete picture than total testosterone alone, especially when SHBG levels are abnormal.
| Population | Reference Range | Notes |
|---|---|---|
| Adult men (total testosterone) | 300-1000 ng/dL | Mayo Clinic reference range; varies by lab methodology |
| Adult men (free testosterone) | 70-141 pg/mL | Calculated values; may vary based on SHBG and albumin levels |
| Adult men (SHBG) | 13-57 nmol/L | Increases with age; affects testosterone availability |
| Adult men (albumin) | 3.5-5.2 g/dL | Used in free testosterone calculations |
Reference ranges shown are general guidelines. Your lab report will include the specific reference range used by the laboratory that processed your sample, which is the authoritative range for interpreting your results.
What does a “Low” result mean?
Low total testosterone may indicate hypogonadism, pituitary disorders, or other hormonal imbalances. Low SHBG can be associated with insulin resistance, obesity, or metabolic syndrome, though it may increase free testosterone availability. Low albumin may suggest liver disease, kidney problems, or malnutrition.
What does a “High” result mean?
Elevated total testosterone may indicate testicular tumors, adrenal gland disorders, or use of testosterone supplements. High SHBG can reduce the amount of available free testosterone despite normal total levels, potentially causing symptoms of low testosterone. Elevated albumin may suggest dehydration or other health conditions.
Privacy & confidentiality
Your test results are delivered confidentially through your secure online account. Results are not shared with employers, insurance companies, or anyone else without your explicit consent. All testing is conducted with complete privacy and discretion.
Frequently asked questions
CPT Code: 84403, 84402, 84270, 82040
This test may not be available in: NY, NJ, RI
This page is for informational purposes only and does not constitute medical advice. Always consult with a healthcare provider regarding any health concerns. LevelPanel does not diagnose, treat, or prescribe.
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Not sure if this is the right test? Contact our care team for guidance.